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A few comments.

I don't know anything about top pop songs but in every area of activity there are paradigms that develop that people follow, until suddenly a disruptor appears. That's a lovely photo of MD.

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808358: How can anyone who thinks not see this as stupid? If you use wrong filters on structured searches you get wrong answers.

"Big Pharma Never Misses a Trick" just wait till they find a way to patent breathing when wearing a mask.

"Do Acid Reflux Meds Cause Dementia? I read this article aloud to MD, and she responded with, “Well, it might not be the drugs directly. It could well be all the stuff the drugs allow people to eat".” I think this is a world view that MD has: always think of alternative explanations. In quantitative science I always do a rough estimate to confirm a detailed answer. Always find some way to check an answer.

"GLP-1 Agonists in the News. "It isn’t so much about willpower: It’s about biology"." I think we agree with this though not the analysis that follows. You have often posted pictures of people from 50+ years ago. The big question should be why that "set point" has changed.

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Thanks for the commentary. It is true that MD has an alternative way of looking at things, which doesn't help when I come up with a lame excuse for something I screwed up.

I agree about the set point issue. Genes can't change that quickly, so the photos from 50 years ago tell us something has happened environmentally to drive the massive increase in obesity.

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You and MD are a good team. It could be that there are epigenetic set points. The Dutch Hunger Winter (44–45) illustrates that; again, environmental.

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