Hello everyone. Greetings from Montecito. Note: I’m getting the ‘this is too long to be sent as an email’ message. So if you don’t get it in full, click on the view online link in the upper right and read it there. Also, in the early days of The Arrow
Every other driver becomes an idiot, when you don’t leave home on time. And driving 80-85 mph on the freeway? That’s endangering lives, and, frankly, not impressive.
1. Thanks for another good post. The ketogenic diet section bears re-reading by me.
2. M.E. wrote: "click on the view online link in the upper right" You can certainly do it that way.
Or you can simply click the "Arrow #101" title, which is also a direct link to substack.
3. ChatGTP is an *amazing* accomplishment. But it's amazing because its natural language interface is so good. As an analogy, 10-year-olds are amazing in the same way. They can understand when you speak and they can respond in meaningful ways (when in the right mood :-).
But I don't expect ChatGTP to know anything, just as I don't expect a 10 y.o. to know very much. ChatGTP is most certainly not a software Oracle That Knows All, like the omniscient COMPUTER that Mr. Spock & Cap'n Kirk used in '60s StarTrek episodes. ChatGTP doesn't "think" beyond understanding questions and formulating replies. Its responses are based on whatever knowledge it gets from its sources. Hence the mealy-mouthed responses to your vaccine questions.
So is ChatGTP reliable? It's only as reliable as its consensus-built sources are. It can't give a better answer than the best human answer, in other words. And since the efficacy and side-effects of COVID vaccines are still being debated, I wouldn't rely on ChatGTP for information about vaccines. We'd might as well ask it, "What's the best form of government?"
The best overall analogy for ChatGTP is to imagine an Encyclopedia Britannica that understands ordinary questions. Or imagine a natural language interface for web searches. The information you get from either of those is only as good as its authors have made it. In this regard, ChatGTP is yet another example of the G.I.G.O. rule: garbage in, garbage out.
All that said, a good friend of mine has been playing around with ChatGTP both to analyze and to generate computer code. My friend had written some code to calculate lunar ephemerides a couple of years ago. When he submitted that code to ChatGTP, it correctly identified the code's purpose, and without comments in the code or any other hints. What ChatGTP can do in the software realm is revolutionary.
4. A few newsletters back, one of your readers submitted images of fraternity & sorority members that she'd found on the web. I didn't mention it at the time, but the site the reader sent you / us to is very similar to ChatGTP.
The purpose of that site was to generate images based on natural language input. For example, you might tell it: "show me a cat riding a bicycle" or "show me a red moon, a blue moon, and a yellow moon in orbit" and it would respond with images of those things. Sites like these are called "AI text to image" and here's an example of one: https://deepai.org/machine-learning-model/text2img
My point is that ChatGTP responds to text by generating text. The AI text-to-image sites respond to text by generating images. But they're both doing the same type of natural language interpretation to determine how to respond. And again, the amazing thing about the AI-image site is not its artistry; the amazing thing is the site's ability to understand your text requests.
Dr., the results on ketone bodies improving ejection fracture is quite interesting. I've read you a long time but I don't recall you talking much about Vitamin E. The Shute brothers (Canadian doctors practicing between the 1930s and 1970s) used vit E to great effect in treating CAD. I'll point you to their book at the internet archive (hard to find a real copy anymore).
Check out chapter 7 of that book (Dr. Wilfrid E. Shute's Complete Updated Vitamin E Book) adnd you'll see the research that was performed decades ago proving vit E is an antithrombin, antioxidant (which it's primarily known for now), amongst other characteristics. It's antioxidant properties are probably as effective as the ketone bodies... they'd be an interesting one-two punch where ketones improve flow and vit E reduces the tissue's needs for oxygen (alternately, it binds with PUFA to prevent its oxidation thereby sparing more oxygen for the tissues).
Anyway, fascinating stuff that we don't hear nearly enough about. My cardiologist laughs at me when I talk to him about vit E, vit C, Dr. Kendrick's "The Clot Thickens" with its alternate hypthesis, etc. Yes, yes, I should find a new one but I fear most of them worship at the altar of the lipid hypothesis exclusively. Sigh.
I have heard (not sure where) that the heart muscle prefers to run on ketones vs glucose, and will preferentially take ketones from the blood before other parts of the body get a chance ..? And that maybe angina heart pain is similar to the lactic acid build up in muscles after exertion and being forced to run on glucose vs ketones? Not sure if that’s the case or not, but just thought I’d put it out there for discussion 😀. Loving the newsletter - have been following since it had no name. 🥰
I'm a long time reader, Dr. Mike, but sometimes your first world problems (not being able to drive your Tesla 85 miles an hour on the freeway) strike me as rather tone deaf.
I'd love to know more about the ejection fraction improvement with BHB. Does one need to keep their ketones at that level all the time? I have left-ventricular non-compaction and while I'm currently (and have always been) asymptomatic and quite healthy (mine was discovered only upon imaging after sister and mom were symptomatic and diagnosed with it), I have seen my ejection fraction decline by 7% (from 70% to 63%) in the past two years and this bothers me. I'm not keto but definitely high protein+low carb. Curious if focusing on ketosis more could improve my EJ or at the very least slow its decline. Updating my echo and cardiac MRI tomorrow so this was a timely email!
Sorry for the late comment. Just now reading. The bitchute video makes my blood boil. I hope plenty of people of influence are now working on uncovering all the cover ups the past 3 years. And yes I’ve known several who probably wouldn’t have died if they had received HDC early and NOT received RDV in the hospital. What a waste.
Working on converting my elderly parents to Keto. Dad with afib, spinal stenosis and now Parkinson’s. Seeing some results that they are attributing to Levadopa. But I think the diet changes are helping just as much.
Here's an article about ChatGTP from the Saturday New York Times: "The New Chatbots Could Change the World. Can You Trust Them?" It's a layman's view for those interested.
Do you think there is some degree of heart damage sustained with every dose of the vaccine? Unfortunately I had two doses of the modera vaccine before going low carb and waking up to the horrible healthcare bs.
So the drivers who actually comply with the traffic laws are the vax brain idiots. It’s the Dr Eades of the world, who treat traffic laws as a mere suggestion, and believe it’s simply up to them which traffic laws they should comply with and which ones they are free to ignore; those are the right thinking folks. I thought a doctor would be aware of the tremendous toll in death and injuries traffic accidents produce on an annual basis. And the two major causes of traffic fatalities - intoxicated driving and driving at EXCESSIVE speed. First do no harm, good doctor. If it’s perfectly okay for you to violate a traffic law, what of the drivers who choose to ignore stop signs & traffic lights. That okay too? . Why don’t you sit down and calculate just exactly how much time you save by speeding and putting others in harms way - it’s minimal, especially in Southern Cal. Try leaving a bit earlier. And by all means stop denigrating that portion of the population who choose to follow the laws.
Regarding the Trump quote about hydroxychloroquine. Not only did it not help his case that it was Trump, but also he's just so terrible about regurgitating facts he may have heard, that he made it sound really stupid. Thereby making it even easier to make fun of him and his recommendation.
Disclosure: even as a recovering liberal, I still loathe Trump.
Every other driver becomes an idiot, when you don’t leave home on time. And driving 80-85 mph on the freeway? That’s endangering lives, and, frankly, not impressive.
I haven't counted the words, but your posts feel shorter since you joined Substack.
1. Thanks for another good post. The ketogenic diet section bears re-reading by me.
2. M.E. wrote: "click on the view online link in the upper right" You can certainly do it that way.
Or you can simply click the "Arrow #101" title, which is also a direct link to substack.
3. ChatGTP is an *amazing* accomplishment. But it's amazing because its natural language interface is so good. As an analogy, 10-year-olds are amazing in the same way. They can understand when you speak and they can respond in meaningful ways (when in the right mood :-).
But I don't expect ChatGTP to know anything, just as I don't expect a 10 y.o. to know very much. ChatGTP is most certainly not a software Oracle That Knows All, like the omniscient COMPUTER that Mr. Spock & Cap'n Kirk used in '60s StarTrek episodes. ChatGTP doesn't "think" beyond understanding questions and formulating replies. Its responses are based on whatever knowledge it gets from its sources. Hence the mealy-mouthed responses to your vaccine questions.
So is ChatGTP reliable? It's only as reliable as its consensus-built sources are. It can't give a better answer than the best human answer, in other words. And since the efficacy and side-effects of COVID vaccines are still being debated, I wouldn't rely on ChatGTP for information about vaccines. We'd might as well ask it, "What's the best form of government?"
The best overall analogy for ChatGTP is to imagine an Encyclopedia Britannica that understands ordinary questions. Or imagine a natural language interface for web searches. The information you get from either of those is only as good as its authors have made it. In this regard, ChatGTP is yet another example of the G.I.G.O. rule: garbage in, garbage out.
All that said, a good friend of mine has been playing around with ChatGTP both to analyze and to generate computer code. My friend had written some code to calculate lunar ephemerides a couple of years ago. When he submitted that code to ChatGTP, it correctly identified the code's purpose, and without comments in the code or any other hints. What ChatGTP can do in the software realm is revolutionary.
4. A few newsletters back, one of your readers submitted images of fraternity & sorority members that she'd found on the web. I didn't mention it at the time, but the site the reader sent you / us to is very similar to ChatGTP.
The purpose of that site was to generate images based on natural language input. For example, you might tell it: "show me a cat riding a bicycle" or "show me a red moon, a blue moon, and a yellow moon in orbit" and it would respond with images of those things. Sites like these are called "AI text to image" and here's an example of one: https://deepai.org/machine-learning-model/text2img
My point is that ChatGTP responds to text by generating text. The AI text-to-image sites respond to text by generating images. But they're both doing the same type of natural language interpretation to determine how to respond. And again, the amazing thing about the AI-image site is not its artistry; the amazing thing is the site's ability to understand your text requests.
Dr., the results on ketone bodies improving ejection fracture is quite interesting. I've read you a long time but I don't recall you talking much about Vitamin E. The Shute brothers (Canadian doctors practicing between the 1930s and 1970s) used vit E to great effect in treating CAD. I'll point you to their book at the internet archive (hard to find a real copy anymore).
https://archive.org/details/drwilfrideshutes00shut/page/100/mode/2up
Check out chapter 7 of that book (Dr. Wilfrid E. Shute's Complete Updated Vitamin E Book) adnd you'll see the research that was performed decades ago proving vit E is an antithrombin, antioxidant (which it's primarily known for now), amongst other characteristics. It's antioxidant properties are probably as effective as the ketone bodies... they'd be an interesting one-two punch where ketones improve flow and vit E reduces the tissue's needs for oxygen (alternately, it binds with PUFA to prevent its oxidation thereby sparing more oxygen for the tissues).
Anyway, fascinating stuff that we don't hear nearly enough about. My cardiologist laughs at me when I talk to him about vit E, vit C, Dr. Kendrick's "The Clot Thickens" with its alternate hypthesis, etc. Yes, yes, I should find a new one but I fear most of them worship at the altar of the lipid hypothesis exclusively. Sigh.
Here’s a little typo for you: “The paper mainly discusses the affect that ketones have on the endothelium” - “affect” should be “effect”.
I have heard (not sure where) that the heart muscle prefers to run on ketones vs glucose, and will preferentially take ketones from the blood before other parts of the body get a chance ..? And that maybe angina heart pain is similar to the lactic acid build up in muscles after exertion and being forced to run on glucose vs ketones? Not sure if that’s the case or not, but just thought I’d put it out there for discussion 😀. Loving the newsletter - have been following since it had no name. 🥰
I'm a long time reader, Dr. Mike, but sometimes your first world problems (not being able to drive your Tesla 85 miles an hour on the freeway) strike me as rather tone deaf.
This may be the first argument I've seen for exogenous ketones that makes sense.
any projections as to a publication date for Protein Power 2.0 - eagerly awaiting it
I'd love to know more about the ejection fraction improvement with BHB. Does one need to keep their ketones at that level all the time? I have left-ventricular non-compaction and while I'm currently (and have always been) asymptomatic and quite healthy (mine was discovered only upon imaging after sister and mom were symptomatic and diagnosed with it), I have seen my ejection fraction decline by 7% (from 70% to 63%) in the past two years and this bothers me. I'm not keto but definitely high protein+low carb. Curious if focusing on ketosis more could improve my EJ or at the very least slow its decline. Updating my echo and cardiac MRI tomorrow so this was a timely email!
Sorry for the late comment. Just now reading. The bitchute video makes my blood boil. I hope plenty of people of influence are now working on uncovering all the cover ups the past 3 years. And yes I’ve known several who probably wouldn’t have died if they had received HDC early and NOT received RDV in the hospital. What a waste.
Working on converting my elderly parents to Keto. Dad with afib, spinal stenosis and now Parkinson’s. Seeing some results that they are attributing to Levadopa. But I think the diet changes are helping just as much.
Here's an article about ChatGTP from the Saturday New York Times: "The New Chatbots Could Change the World. Can You Trust Them?" It's a layman's view for those interested.
Link is *not* paywalled, no subscription needed .
https://www.nytimes.com/2022/12/10/technology/ai-chat-bot-chatgpt.html?unlocked_article_code=5d3mRdGn-FFrgpTE2oVIOhZAmnx6kLwBTYSRTaAxEMWYSty6H9lMVZRTYwAaaSZIBhnGoZEpK-sG3FGAJk3qw54pTh3BuMaSAFLZY42y1vzy98cDPVWwDFI7IzqBLYPQjhJb41ZTxcNiV-dT8gxrPxfmsOoM7Zpo7_3KR2qu989L8DTycSlfbmpJtQzr3apupKMDoYz5uhFFtaBOlZOPMXaP6dF5FmzMy9go-9h5oL1tbMwmhtdlftAHV9MM-z3bo4yoWuPbIx9eui-O1u5nyyWf9D0da3SCEyMAvpzQ99PaldkPsvrxphZJg-SGuTwtnz7Js6kZJoUJn_bCuxN2ZMQ&smid=share-url
Do you think there is some degree of heart damage sustained with every dose of the vaccine? Unfortunately I had two doses of the modera vaccine before going low carb and waking up to the horrible healthcare bs.
So the drivers who actually comply with the traffic laws are the vax brain idiots. It’s the Dr Eades of the world, who treat traffic laws as a mere suggestion, and believe it’s simply up to them which traffic laws they should comply with and which ones they are free to ignore; those are the right thinking folks. I thought a doctor would be aware of the tremendous toll in death and injuries traffic accidents produce on an annual basis. And the two major causes of traffic fatalities - intoxicated driving and driving at EXCESSIVE speed. First do no harm, good doctor. If it’s perfectly okay for you to violate a traffic law, what of the drivers who choose to ignore stop signs & traffic lights. That okay too? . Why don’t you sit down and calculate just exactly how much time you save by speeding and putting others in harms way - it’s minimal, especially in Southern Cal. Try leaving a bit earlier. And by all means stop denigrating that portion of the population who choose to follow the laws.
Regarding the Trump quote about hydroxychloroquine. Not only did it not help his case that it was Trump, but also he's just so terrible about regurgitating facts he may have heard, that he made it sound really stupid. Thereby making it even easier to make fun of him and his recommendation.
Disclosure: even as a recovering liberal, I still loathe Trump.
You asked for typo alerts. Here are some phrases that need fixing:
'Other than breath oxygen from a cylinder' (should be breathe)
'he quit to go college'
'Her dad asked my why '